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PARNZOLEIX™ - DSR CAPSULES

Pantoprazole Gastro-resistant 40MG and Domperidone (SR) 30MG Capsules IP

PACKING SIZE / TYPE

10x10 Alu Alu Pack

Summary

PARNZOLEIX™ - DSR CAPSULES is a combination medication designed to manage and relieve symptoms associated with gastroesophageal reflux disease (GERD) and related conditions, such as acid reflux, heartburn, and nausea. Each tablet contains Pantoprazole 40 mg, a proton pump inhibitor that reduces stomach acid, and Domperidone 30 mg, a dopamine antagonist that promotes gastrointestinal motility, alleviating symptoms like bloating and nausea.

Side Effects

Common side effects of PARNZOLEIX™ - DSR CAPSULES may include:

  • Headache
  • Dizziness
  • Diarrhea or constipation
  • Dry mouth
  • Stomach discomfort or gas
  • Fatigue

Severe side effects (rare):

  • Severe allergic reactions (e.g., rash, itching, swelling)
  • Unusual changes in heartbeat
  • Severe abdominal pain
  • Persistent diarrhea

If any of these severe side effects occur, seek medical attention immediately.

Usage

PARNZOLEIX™ - DSR CAPSULES are commonly prescribed for:

  • Gastroesophageal Reflux Disease (GERD)
  • Acid reflux and heartburn
  • Nausea and vomiting associated with gastric discomfort
  • Gastric motility disorders

Concerns

  • Pregnancy: Consult your doctor before using this medication if you are pregnant, as it may not be suitable during pregnancy.
  • Breastfeeding: The drug is excreted in breast milk; consult a healthcare professional if you are breastfeeding.
  • Liver Disease: Patients with liver dysfunction should use PARNZOLEIX™ - DSR CAPSULES cautiously, and dose adjustments may be necessary.
  • Kidney Disease: If you have any kidney issues, talk to your doctor to evaluate the safety and appropriate dose.

When not to use?

PARNZOLEIX™ - DSR CAPSULESshould not be used in the following conditions:

  • Allergy or hypersensitivity to Pantoprazole, Domperidone, or any of the tablet components.
  • Severe liver impairment or liver failure.
  • Gastrointestinal bleeding or obstruction.
  • Prolonged QT syndrome or heart conditions.
  • Children under the age of 12 years (unless specifically prescribed by a doctor).

Warnings

  • Prolonged Use: Prolonged use of Pantoprazole can lead to vitamin B12 deficiency or magnesium deficiency. Regular monitoring is advised.
  • Cardiac Concerns: Domperidone may affect heart rhythm and should be used cautiously in patients with pre-existing heart conditions.
  • Interactions: PARNZOLEIX™ - DSR CAPSULES can interact with several other drugs, including anticoagulants, antifungals, and other gastrointestinal medications. Always inform your doctor about all the medications you are taking.
  • Alcohol: It is recommended to avoid alcohol while using PARNZOLEIX™ - DSR CAPSULES as it may worsen side effects such as dizziness or nausea.

Dosage

  • Recommended Dose: 1 tablet per day, preferably in the morning before food.
  • Missed Dose: If you miss a dose, take it as soon as you remember, unless it’s almost time for your next dose. Do not take double doses to make up for a missed one.

Interactions

PARNZOLEIX™ - DSR CAPSULESmay interact with several other medications, including:

  • Antacids: Can reduce the effectiveness of Pantoprazole if taken together.
  • Blood thinners: May interact with warfarin, increasing the risk of bleeding.
  • Antifungal drugs: Medications like ketoconazole may interfere with Pantoprazole’s absorption.
  • CNS depressants: Domperidone may enhance the sedative effects of CNS depressants, such as benzodiazepines.
  • Antibiotics: Antibiotics such as clarithromycin may interact with Pantoprazole.

General Instructions

  • Always follow your doctor's prescription and do not self-medicate.
  • Inform your doctor if you are pregnant, breastfeeding, or have any pre-existing medical conditions.
  • Avoid sudden discontinuation of the medication to prevent a relapse of symptoms.
  • Keep the tablets stored in a cool, dry place, away from direct sunlight, and out of reach of children.

Other Details

  • Packaging: PARNZOLEIX™ - DSR CAPSULES are available in strip packaging containing 10 tablets per strip.
  • Shelf Life: 24 months from the date of manufacturing.

References

  • Borchard, G. et al. (2006). Clinical Pharmacokinetics of Pantoprazole and Its Therapeutic Application. Therapeutic Drug Monitoring.
  • Domperidone in Gastrointestinal Motility Disorders: A Review of Clinical Applications. Journal of Clinical Gastroenterology.
  • Pasternak, G., & Yahalom, G. (2014). Effects of Domperidone in Gastrointestinal Disorders. American Journal of Gastroenterology.
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